Concerta methylphenidate 18mg, 36mg, 54mg
Concerta (Generic Name: methylphenidate HCl ER) is an extended release delivery system. central systema nervosum stimulant ADHD medication that’s primarily wont to treat attention deficit hyperactivity disorder (ADHD or ADD) in children ages 6-12, adolescents, and adults up to age 65. Abive all, Concerta doses may improve focus for people with inattentive ADHD. Also, decrease impulsivity and hyperactive behavior — hallmark ADHD symptoms for several patients
Clinical Pharmacology of methylphenidate
To start with, Methylphenidate HCl may be a central systema nervosum (CNS) stimulant. Also, No known mode of therapeutic action in Attention Deficit Hyperactivity Disorder (ADHD). However, Methylphenidate is assumed to dam the reuptake of norepinephrine and dopamine into the presynaptic neuron. Also it increase the discharge of those monoamines into the extraneuronal space.
Methylphenidate-readily absorbed. Following oral administration of concerta 27 mg, plasma methylphenidate concentrations increase rapidly. most significantly , reaching an initial maximum of about 1 hour. Followed by gradual ascending concentrations over subsequent 5 to 9 hours after which a gradual decrease begins. Mean times to succeed in peak plasma
concentrations across all doses of CONCERTA® occurred between 6 to 10 hours.
Indication and usage
Attention Deficit Hyperactivity Disorder (ADHD) CONCERTA® is indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD). However, the efficacy of CONCERTA® within the treatment of ADHD was established in three controlled trials. Moreover, this included children aged 6-12 and in one controlled trial in adolescents aged 13-17.
What Is the simplest Dosage for Concerta?
Above all, the optimal dosage of Concerta varies by patient. Certainly, Concerta capsules are available in 18mg, 27mg, 36mg, and 54mg dosages. However, the time-release formulation designed to take care of an ever-increasing blood level of medication. additionally , FDA guidance suggests a maximum 54mg daily dose for youngsters and adolescents, and 72mg daily for adults.
Contraindication of concerta
Hypersensitivity to Methylphenidate
Tics in patients with motor tics or with Tourette’s syndrome
Monoamine Oxidase Inhibitors
Serious Cardiovascular Events
Hypertension and Other Cardiovascular Conditions